ANNEXIN II Meaning and
Definition
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Annexin II, also known as Annexin A2, is a protein that plays a significant role in the regulation of various cellular processes. It is part of the annexin family of calcium-binding proteins characterized by their ability to bind to negatively charged phospholipids in a calcium-dependent manner.
In a cellular context, Annexin II is primarily found at the cell membrane where it acts as a linker between the cell's cytoskeleton and the plasma membrane. This function is crucial for maintaining the structural integrity of cells and facilitating their movement. Annexin II has been implicated in cellular processes such as endocytosis, exocytosis, cell adhesion, and membrane repair.
Furthermore, Annexin II has been identified as a receptor for tissue plasminogen activator (tPA), which is involved in the regulation of the fibrinolytic system. Through its interaction with tPA, Annexin II contributes to the conversion of plasminogen to plasmin, an enzyme responsible for the degradation of blood clots.
Research has shown that Annexin II is implicated in several physiological and pathological conditions, including cancer metastasis, inflammation, and autoimmune disorders. Dysregulation of Annexin II expression or function has been associated with various diseases, making it a potential target for therapeutic interventions.
In summary, Annexin II is a calcium-binding protein involved in maintaining cellular structure, facilitating membrane-related processes, and contributing to the regulation of the fibrinolytic system.
Common Misspellings for ANNEXIN II
- annexini
- znnexin ii
- snnexin ii
- wnnexin ii
- qnnexin ii
- abnexin ii
- amnexin ii
- ajnexin ii
- ahnexin ii
- anbexin ii
- anmexin ii
- anjexin ii
- anhexin ii
- annwxin ii
- annsxin ii
- anndxin ii
- annrxin ii
- ann4xin ii
- ann3xin ii
- annezin ii
Etymology of ANNEXIN II
The word "Annexin" is derived from the Latin word "annexus", which means "to join" or "to connect". It refers to a family of calcium-dependent phospholipid-binding proteins present in eukaryotic organisms.
The Roman numeral "II" indicates that "Annexin II" is the second member of the Annexin protein family to be discovered and characterized.
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